Phytochemicals from Achillea fragrantissima are Modulators of AβPP Metabolism

Title: Anti-neuroinflammatory Effects of the Extract of Achillea Fragrantissima

Statistical review: Yes, but I do not feel adequately qualified to assess the statistics.

Anti-Neuroinflammatory effects of the extract of Achillea fragrantissima

BACKGROUND The neuroinflammatory process plays a central role in the initiation and progression of neurodegenerative diseases such as Parkinson's and Alzheimer's diseases, and involves the activation of brain microglial cells. During the neuroinflammatory process, microglial cells release proinflammatory mediators such as cytokines, matrix metalloproteinases (MMP), Reactive oxygen species (ROS)...

Extract of Achillea fragrantissima Downregulates ROS Production and Protects Astrocytes from Oxidative-Stress-Induced Cell Death

Phytochemicals as modulators of neoplastic phenotypes.

It is generally accepted that nutritional behaviors constitute decisive components of human health. Phytochemicals (small, nonenergetic molecules of vegetal origin) are overall inhibitory on the expression of gene products promoting proliferation and resistance to apoptosis. On the contrary, phytochemicals stimulate the synthesis of adaptive proteins that favor resistance to cellular stress (de...

Phytochemicals as Modulators of PPARs and RXRs

Welcome to this special issue of PPAR Research on " Phyto-chemicals as modulators of PPARs and RXRs. " Plants have played a crucial role in the prevention and treatment of human diseases for thousands of years. A significant number of contemporary drugs with high efficacy are derived from herbal origin. These natural phytochemicals, including certain nutrients, are therefore of great medicinal ...